Microfiber releasing into urban rivers from face masks during COVID-19COVID-19 동안 안면 마스크에서 도시 강으로 방출되는 극세사Article Published on 2022-10-012022-09-11 Journal: Journal of environmental management [Category] COVID19(2023년), SARS, 치료기술, [키워드] aggravate Analysis aquatic environment cause Contamination coronavirus disease COVID-19 COVID-19 pandemic density element Epidemic evaluate expected face Face mask Face masks immersion investigated Mask Medical waste management Microfiber Occurrence plastic Plastic degradation potentially toxic Prevent protective role Public Public awareness raise released Respirator river River management SEM SEM analysis. significantly higher Spread spread of COVID-19 Tear tested Transport vector water wear wear and tear [DOI] 10.1016/j.jenvman.2022.115741 PMC 바로가기 [Article Type] Article
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment managementReview article Published on 2022-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome addition aggravate Asymptomatic caused Characteristics chronic liver disease cirrhosis clinical clinical manifestation Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient Critical death disease dysfunction Epidemic extrapulmonary organs Factors hepatic function Hepatocellular carcinoma hypoxia immune increased risk infection with SARS-CoV-2 inflammatory factor storms Injury liver Liver damage Liver disease liver enzyme Liver function Liver injury liver transplant Liver transplantation management mechanism nonalcoholic fatty liver pathophysiological mechanism Patient patients prevalent public health reperfusion Respiratory disease risk SARS-CoV-2 severe disease Stress Treatment Vaccine [DOI] 10.1016/j.biopha.2022.113568 [Article Type] Review article
Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivationArticle Published on 2022-09-142022-11-16 Journal: Signal Transduction and Targeted Therapy [Category] SARS, 유전자 메커니즘, [키워드] activated Activation acute respiratory syndrome Adenovirus aggravate Aggravated alleviate complement Complement pathway contribute coronavirus Coronaviruses expressing highly pathogenic human coronaviruses Hyperactivation in vitro in vivo Inflammation inflammatory lung injury Inflammatory response Interaction lectin pathway Lung injury MASP-2 mechanism MERS-CoV mice N protein Pathogenesis pathogenic coronavirus Pneumonia respiratory syndrome coronavirus resulting SARS-CoV SARS-CoV-2 SARS-CoV-2-infected patients serine protease significantly suggested the N protein Therapeutic approach These data [DOI] 10.1038/s41392-022-01133-5 PMC 바로가기
Clinical factors affecting depression in patients with painful temporomandibular disorders during the COVID-19 pandemic Research Published on 2022-08-292022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] Affect affecting aggravate Anxiety arthralgia assessment axis BAI Beck clinical clinical factors COVID-19 COVID-19 pandemic Depression diagnosed disorder Factor Factors female females high correlation increase in intensity inventory investigated moderate multifactorial Multiple regression analysis myalgia negatively affected Novel coronavirus Pain pandemic Patient physical positively correlated Psychological Psychological distress recent Sex significantly significantly increased Stress stress level temporomandibular disorder TMD TMD pain was recorded [DOI] 10.1038/s41598-022-18745-0 [Article Type] Research
Co-existence and co-infection of influenza A viruses and coronaviruses: public health challengesReview article Published on 2022-08-172022-10-05 Journal: The Innovation [Category] 비임상, [키워드] acute respiratory syndrome affecting aggravate Alter both virus caused circulation co-existence Co-infection coronavirus CoV CoVs Cross-species transmission disease disease transmission Evolution facilitate FIVE Genetic host range hosts Human IAV influenza A virus influenza A virus maintain Pandemics public health public health challenges Recombination risk SARS-CoV-2 Surveillance variant virus [DOI] 10.1016/j.xinn.2022.100306 [Article Type] Review article
TRPC6 is altered in COVID-19 pneumoniaTRPC6은 COVID-19 폐렴에서 변경됩니다.Article Published on 2022-08-012022-09-11 Journal: Chemico-biological interactions [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] aggravate alveolar septa anatomical Capillaries cellular ciliated ciliated epithelium cough COVID COVID pneumonia COVID-19 COVID-19 pneumonia Dissection dissections distribution drugs Fever fibrosis Gene Expression Human human lung human lung tissue hyaline membrane hyaline membranes immunohistochemistry Inflammation inflammatory lesions inhibiting investigated involved lesions lung lung; molecular mechanism molecular mechanisms observation observations patients with COVID-19 Pneumonia pneumoniae processed Protein pulmonary inflammation reported Support Symptom target Therapies Therapy. tissue tissues TRP TRPC6 TRPC6 channels vessel wall was obtained [DOI] 10.1016/j.cbi.2022.109982 PMC 바로가기 [Article Type] Article
Serum concentration of extracellular cold-inducible RNA-binding protein is associated with respiratory failure in COVID-19Observational Study Published on 2022-07-292022-10-05 Journal: Frontiers in Immunology [Category] 임상, [키워드] adjusted age aggravate association BMI Chest computed tomography Chest CT CIRP Cohort Comorbidity Concentration contribute correlated correlation COVID-19 damage-associated molecular pattern DAMP DAMPs defined determine disease dysregulated eCIRP evaluate external validation Extracellular extracellular CIRP FiO2 HFNO High-flow nasal oxygen highest Hospitalized hospitalized patient Host immune response Hypoxemia induce Inflammation inflammatory biomarkers Linear regression lung involvement mechanical ventilation Mild oxygen Pathogenesis Patient patients with COVID-19 peak prospective observational study Protein pulmonary involvement reduce Respiratory failure Respiratory Support risk Sepsis serum Serum level severe COVID-19 severe hypoxemia severity Severity of disease Severity. Sex suggested symptom duration tissue injury Treatment uncontrolled university was used were used [DOI] 10.3389/fimmu.2022.945603 PMC 바로가기 [Article Type] Observational Study
Urban monitoring, evaluation and application of COVID-19 listed vaccine effectiveness: a health code blockchain studyCOVID-19 등재 백신 효과의 도시 모니터링, 평가 및 적용: 건강 코드 블록체인 연구Article Published on 2022-07-132022-09-11 Journal: BMJ Open [Category] 변종, [키워드] aggravate Algorithm analysed Analysis Asymptomatic average basic reproduction number calculate city Complete conditions Contact cooperation country COVID-19 decrease deviation Effectiveness eight ENhance epidemiological Epidemiological investigation Epidemiology evaluate greater Health Health policy Health policy. herd immunity Immunity increase Incubation period index infection rate information measure MONITOR mutant virus not decreased outcome Patient Primary outcome Primary outcomes promote promoted proportion protective effect reduced regions respond second significantly Simulation statistical symptomatic the vaccine this system transmitted urban urban population vaccination vaccination rate Vaccination strategy Vaccine Vaccines variant Variation virus weight [DOI] 10.1136/bmjopen-2021-057281 PMC 바로가기 [Article Type] Article
Super Dominant Pathobiontic Bacteria in the Nasopharyngeal Microbiota Cause Secondary Bacterial Infection in COVID-19 Patients비인두 미생물총의 슈퍼 우세한 병원성 박테리아는 COVID-19 환자에서 2차 박테리아 감염을 유발합니다Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] 16S rRNA 16S rRNA gene abundance accounted Acinetobacter aggravate analyzed Bacterial Bacterial infection bacterial pneumonia bacterial specy cause collected Community composed coronavirus disease Coronavirus disease 2019 Corynebacterium Coverage COVID-19 COVID-19 infection COVID-19 patient defined difference disease severity Diversity dominant fatality genus High-throughput sequencing Infection Influenza invasive Lower respiratory tract lower respiratory tract samples microbiota Mild mild COVID-19 patients mild infection mild infections nasopharyngeal nasopharyngeal microbiota nasopharynx pathobiontic bacteria pathogen Patient patients patients with SARS-CoV-2 Pneumonia previous study respiratory infectious disease respiratory tracts responsible rRNA Sample SARS-COV-2 infection secondary secondary bacterial infection secondary bacterial infection. secondary bacterial pneumonia Seven severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients severe group severe pneumonia significantly significantly higher Staphylococcus upper upper and lower respiratory tracts upper respiratory tract variety was used [DOI] 10.1128/spectrum.01956-21 PMC 바로가기 [Article Type] Article
Efficacy of short-course colchicine treatment in hospitalized patients with moderate to severe COVID-19 pneumonia and hyperinflammation: a randomized clinical trialRandomized Controlled Trial Published on 2022-06-022022-10-04 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] Admission aggravate anti-inflammatory treatment applied Arm benefit clinical benefit Colchicine colchicine group colchicine treatment components CPAP Cytokine storm syndrome death develop dose Efficacy Endpoint EudraCT hospitalized patient hyperinflammation ICU admission in both groups intensive care Invasive mechanical ventilation investigator-initiated trial mechanical ventilation moderate Most patient Non-invasive observer-blinded occurred outcome outcome measure Patient patients with COVID-19 Pneumonia Primary outcome pulmonary disease Randomized randomized clinical trial Randomly receive Severe COVID-19 pneumonia standard care steroid study population Trial with COVID-19 [DOI] 10.1038/s41598-022-13424-6 PMC 바로가기 [Article Type] Randomized Controlled Trial